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Anti-Oxidants:

 
Vitamin C - STAY-C® 50, Sodium ascorbyl phosphate, the stabilized (phosphorylated) sodium salt of L-ascorbic acid, at an optimal concentration, has been designed to neutralize the oxidative activity of the dissolved oxygen that is present on aqueous vehicles. Vitamin C blocks the 3 free radicals most responsible for cell membrane damage - superoxide, singlet oxygen and hydroxyl. In addition, Vitamin C stimulates the production of collagen and elastin to promote skin softness and elasticity while reducing wrinkling associated with dry skin. When applied topically it becomes an inherent part of the skin and persists for up to 3 days.

  


The benefits:
unlike other forms of Vitamin C, STAY-C® maintains its stability for a longer period
penetrates the skin deeply
has documented positive effects on aging
has been shown to reduce wrinkles in clinical studies
promotes production of collagen I and II


 
     
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Research:

Hiroshi Ikeno, MD; Kitaro Ohmori, MD; Clinical Study if Safety and Efficacy of 5% Sodium L-Ascorbyl-2-Phosphate Lotion to Treat Acne Scars after Glycolic Acid Peels; Cosmetic Dermatology. Vol 16 No. 10, October 2003

Hiroshi Ikeno, MD; Kitaro Ohmori, MD & Tomoyuki Monma; An open study comparing efficacy of 5% sodium L-ascorbyl-2-phosphate lotion versus benzoylpeoxide cream in the treatment of acne vulgaris; Journal of the American Academy of Dermatology. Vol 50, Issue 3, Suppl 1, March 2004, Page P18, Poster Abstract

Ikeno, H, Nishikawa T. Clinical evaluation of topical sodium-L-ascorbyl-phosphate lotion (5% W/V) in patients with acne. Presented at Society for Investigative Dermatology 63rd Annual Meeting, May 15-18, 2002 Los Angeles, California, Abstract

Boyce ST, Supp AP, Swope VB, et al. Vitamin C regulates keratinocycte viability, epidermal barrier, and basement membrane in vitro, and reduces wound contraction after grafting of cultured skin substitutes. J Invest Dermatology 2002; 118:565-572

Savini I, Catani VC, Rossi A, et al. Characterization of keratinocytes differentiation induced by ascorbic acid: protein kinase C involvement and Vitamin C homeostasis. J Invest Dermatology 2002; 118:372-379

Nakayama S, Kobayashi S, et al. Preventative effects of sodium L-ascorbyl-2-phosphate on the development of UVB-induced damage in cultured mouse skin. J Jpn Cosmetic Science Society. 2002;26(suppl):24-28

Hanson K, Clegg R Bioconvertible vitamin antioxidants improve sunscreen photoprotection against UV-induced reactive oxygen species (free radicals); Journal Cosmetic Science, 54, 584-598 (Nov/Dec 2003)

Alster, T: Table Talk:Common Questions about Laser Resurfacing, Dermatological Surgery, Volume 24, p.121-130, 1998

Ames Bruce N, et al: Oxidants, Antioxidants and the Degenerative Diseases of Aging. Proceedings National Academy of Science, USA, Volume 90, p.7915-7922 September 1993

Boschert, Sherry: Topical Product Helps Clear Postlaser Erythema, Skin and Allergy News, Volume 17, Number 10:29, October 1996

Boyera N, Galey I, Bernard BA: Effect of Vitamin C and its derivatives on collagen synthesis and cross-linking by normal human fibroblasts, Int. J. Cosm. Sci. Volume 20, p. 151-158

Darr D, et al:Topical Vitamin C Protects Skin from Ultraviolet Radiation-Induced Damage, British Journal of Dermatology, 247-253 1992

Greco, Richard J and the Plastic Surgery Educational Foundation DATA Committee: Safety and Efficacy Report. Plastic and Reconstructive Surgery, Volume 105, Number 1, January 2000

Nakamura, Toshiako et al: Vitamin C Abrogates the Deleterious Effects of UVB Radiation on Cutaneous Immunity by a Mechanism that does not Depend on TNF-x, The society for Investigative Dermatology, Inc, 20-24, 1997

Pinell, Sheldon P: Vitamin C. Advanced Technology Conference Proceedings: p.34-35, September 1993

Rose, Richard and Bode, Ann: Biology of Free Radical Scavengers: An Evaluation of Ascorbate. The FASEB Journal, Volume 7, p.1135-1142, September 1993

Sakamoto T, Egawa M, Iwai I, Tanaka M, Akiba M, Akaiyama J, Yanamoto I: Development of the New Types of Skincare Cosmetics Containing the Novel Vitamin C Derivative with Prolonged Effects, 19th IFSCC Congress Sydney 1996, 2, p.5-17

Shindo, Yasuko et al: Dose-Response Effects of Acute Ultraviolet Irradiation on Antioxidants and Molecular Makers of Oxidation in Murine Epedermis and Dermis, Journal of Investigative Dermatology, Inc, 470-475, 1994

Shindo, Yasuko et al: Enzymic and Non-Enzymic Antioxidants in Epedermis and Dermis of Human Skin, The Society of Investigative Dermatology, Inc, 122-124, 1994

Takenouchi K and Aso K: The Relation between Melanin Formation and Ascorbic Acid, J. Vitaminol, Volume 10, p.123-134, 1964

Tsuzki T, Masatsuji E, Ito S, Ogata E, Fusyo Y: Protective Effects of Ascorbyl 2-Phosphate against UV-Generated Radicals in Skin, Society of Cosmetic Chemists Annual Scientific Meeting and Technology Showcase, 1999

Traikovich, Steven S: Use of Topical Vitamin C and its Effects on Photodamaged Skin Topography. Archives of Otolaryngology, October 1999

Vitamin C and Derivatives, Total Effects, Scientific Literature Review, excerpts from CIR, August 21, 2000


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Due to the advanced nature of the high performance PRESCRIBED solutions products, the range, is intended for use only under the supervision of physicians and medical personnel. All rights reserved. The statements on this website have not been evaluated by the FDA. The products are not intended to diagnose, treat, cure or prevent any disease. PRESCRIBEDsolutions [CUSTOMIZED SKINCARE] is a registered trademark of PRESCRIBEDsolutions, LLC. Capislow® is a registered trademark of Sederma. Lumedia® and Hylexin® are registered trademarks of Bremenn Research Labs. Pycnogenol, FloraGLO and STAY-C 50 are trademarks of their respective owners. Synovea HR is a registered trademark of Sytheon. Patent Pending. © PRESCRIBEDsolutions, LLC 2001-2007.